|
NONI
 Noni
(Morinda citrifolia) is a fruit-bearing plant native to the
South Pacific that has been used as a traditional medicine – as an
antibacterial/antifungal/antiviral, anti-inflammatory, for high blood
pressure, cancer and immune enhancement – for over 2000 years1.
Most research has
centered on a set of chemicals found in Noni – known as glycosides
–which are believed to be responsible for its therapeutic effects2.
While there are no
controlled clinical studies, Noni has been shown to have a positive
effect on cancer and tumor growth both in cells and animals3-12.
Other studies have validated the traditional use for possible relief of
pain (analgesia) and stress13-14.
Work Cited:
Noni
1. Acta Pharmacol Sin, 23(12):1127-41, 2002. Morinda citrifolia (Noni):
a literature review and recent advances in Noni research.
2. J Nat Prod, 64:799-800, 2001. Iridoid glycosides from the leaves of
Morinda citrifolia.
3. Cancer Lett, 73:161-6, 1993. Induction of normal phenotypes in ras-transformed
cells by damnacanthal from Morinda citrifolia.
4. Proc West Pharmacol Soc, 37:145-6, 1994. Anticancer activity of
Morinda citrifolia (noni) on intraperitoneally implanted Lewis lung
carcinoma in syngeneic mice.
5. Proc West Pharmacol Soc, 39:7-9, 1996 Immunomodulation contributes to
the anticancer activity of morinda citrifolia (noni) fruit juice.
6. Phytother Res, 13:380-7, 1999.An immunomodulatory polysaccharide-rich
substance from the fruit juice of Morinda citrifolia (noni) with
antitumour activity.
7. Ann N Y Acad Sci, 952:161-8, 2001. Cancer preventive effect of
Morinda citrifolia (Noni).
8. Cancer Res, 61:5749-56, 2001. Two novel glycosides from the fruits of
Morinda citrifolia (noni) inhibit AP-1 transactivation and cell
transformation in the mouse epidermal JB6 cell line.
9. Org Lett, 3:1307-9, 2001. A new unusual iridoid with inhibition of
activator protein-1 (AP-1) from the leaves of Morinda citrifolia L.
10. Angiogenesis, 6:143-9, 2003. .Inhibition of angiogenic initiation
and disruption of newly established human vascular networks by juice
from Morinda citrifolia (noni).
11. Phytother Res, 17:1158-64, 2003. Antitumour potential of a
polysaccharide-rich substance from the fruit juice of Morinda citrifolia
(Noni) on sarcoma 180 ascites tumour in mice.
12. Bioorg Med Chem, 11:2499-502, 2003. New unusual iridoids from the
leaves of noni (Morinda citrifolia L.) show inhibitory effect on
ultraviolet B-induced transcriptional activator protein-1 (AP-1)
activity.
13. Planta Med, 56:430-4, 1994.Analgesic and behavioral effects of
Morinda citrifolia.
14. Acta Pharmacol Sin, 22:1084-8, 2001.Antistress effect of
oligosaccharides extracted from Morinda officinalis in mice and rats.
As required by the Food and Drug
Administration:
These statements have not been evaluated by the FDA. This
product is not intended to diagnose, treat, cure or prevent
any disease. |